- Deficiency of insulin secretion, insulin activity, or both.
- Glucose transporter deficiency.
- Or both.
Classify forms of diabetes mellitus :
- Type 1 diabetes, which include simtoma ketoacidosis until the destruction ofbeta cells in the pancreas caused by or causing autoimmunity, and isidiopathic. Diabetes mellitus with unclear pathogenesis, such as cysticfibrosis or the deficiency of mitochondria, are not included in thisclassification.
- Type 2 diabetes, caused by a deficiency of insulin secretion, oftenaccompanied by insulin resistance syndrome
- Gestational diabetes, which includes gestational impaired glucosetolerance, and
- gestational diabetes mellitus GIGT, GDM.and according toclinical stage without consideration of the pathogenesis, made into :
- Diabetes requiring insulin for survival, as in the case of C-peptidedeficiency.
- Diabetes requiring insulin for control. At this stage, endogenousinsulin secretion is not sufficient to achieve normoglicemia symptoms, if notaccompanied by additional hormones from outside the body.
- Not insulin requiring diabetes.
Malnutrion-related classification of diabetes mellitus, MRDM, no longer usedbecause, although malnutrition can affect the expression of several types ofdiabetes, up to now has not found evidence that malnutrition or proteindeficiency can lead to diabetes. MRDM subtypes; protein-deficient pancreaticdiabetes mellitus, PDPDM, PDPD, PDDM, is still regarded as a form ofmalnutrition that was induced by diabetes mellitus and requires furtherresearch. Whereas the other subtypes, Fibrocalculous pancreatic diabetes, FCPD,classified as exocrine pancreatic disease in fibrocalculous pancreatopathy trajectorythat induce diabetes mellitus.
Classification of Impaired Glucose Tolerance, IGT, now defined as the stage ofdefective glucose regulation, as can be observed in all types of aberrationhiperglisemis. But no longer considered diabetic.
Classification of Impaired Fasting glycaemia, IFG, was introduced as the ratiosimtoma fasting blood sugar is higher than the upper limit of normal range, butstill below the ratio determined as the basis for the diagnosis of diabetes.